Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity

2026-10-07来源 Nature NewsEnglish

Nature, Published online: 30 September 2026; doi:10.1038/s41586-026-11087-1

By being restricted to target regions by MLLT1–MLLT3 occupancy, activation-induced deaminase activity is able to avoid most off-target mutagenesis during B cell somatic hypermutation.

原文：https://www.a8q9.cn/en/article/histone-readers-mllt1-and-mllt3-concentrate-aid-to-confer-locus-specificity-41500f.html

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