Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

2026-10-15来源 Nature NewsEnglish

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1

A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.

原文：https://www.a8q9.cn/en/article/engineered-tyk2-dependence-enables-myeloid-selective-il-10-receptor-agonism-593708.html

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