Artificial intelligence-enabled clinical phenotyping of human brown fat

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11162-7

Artificial intelligence-enabled quantification and analyses of brown adipose tissue (BAT) activity uncover links between BAT and a healthier metabolic profile along with lower rates of psychiatric disease, and can identify pharmacologic agents that could be repurposed to activate this tissue in humans.